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 Aptilon Announces AxcelRxSM Live Video Detailing Sales Channel 
with Ortho-McNeil Neurologics, Inc.

 Ortho-McNeil Neurologics, Inc. adds technology-based alternative sales channel linking live sales representatives with key physicians as cornerstone of their sales strategy

Montreal, September 25, 2007 - Aptilon Corporation (TSX.V: APZ), a leading provider of physician access through its innovative alternative sales and marketing channel, today announced that Ortho-McNeil Neurologics, Inc. has selected Aptilon’s AxcelRxSM Live video detailing service to educate physicians about its products. The Internet-based AxcelRx alternative sales channel is a key component of the model that will enable Ortho-McNeil Neurologics representatives to provide convenient “concierge”-type services and education to physicians.

“We place a high priority on meeting the informational needs of our customers. The dynamic healthcare market and growth of technology present us with both a need and opportunity to develop and deliver better customer solutions. Our goal is to lead the industry in delivering meaningful information to customers when, where and how it is most convenient,” said Ortho-McNeil Neurologics Vice President, Marketing, Denice Torres.

Ortho-McNeil Neurologics markets products for Alzheimer's disease, epilepsy, and migraine prevention treatment. Aptilon’s ReachNet physician access network will link target physicians who treat these diseases in live, web-based interactions with Ortho McNeil Neurologics sales representatives supported by a wide range of services.

“We are looking forward to assisting Ortho-McNeil Neurologics build strong relationships with physicians,” said Aptilon President Denis Martineau. “With physicians facing growing demands on their time, there is a corresponding decline in their ability to meet with sales representatives during traditional office hours. AxcelRx Live allows high-quality interactions at the physician’s convenience with live representatives,” continued Martineau. “This new alternative sales channel integrates with the field sales force to address the needs of physicians efficiently and effectively.”

Aptilon’s AxcelRx Live video detailing serves health care professionals when and where they are accessible, even at home, during nights and weekends. Aptilon’s current rep-physician interactions are averaging more than eight minutes for primary care physicians and fifteen minutes for specialists, achieving high levels of physician satisfaction.

Aptilon has successfully enabled large numbers of rep-physician interactions for leading pharmaceutical companies, accessing more than 450,000 opted-in physicians through Aptilon’s ReachNet physician access channel, an extensive network of partner and company-owned websites.

Greg Mattle, manager of Ortho-McNeil Neurologics e-Marketing, said, “The pharmaceutical industry is evolving from mass marketing to relationship marketing. AxcelRx Live enables us to make our brand information and services available to physicians in a way that’s meaningful and impactful. Our commitment in this area is significant.”

About Aptilon Corporation
Aptilon enables pharmaceutical, biotech and medical device companies to effectively reach and interact with physicians via the Internet through its innovative AxcelRx Live video detailing (with company reps), virtual programs, peer selling and other sales and marketing programs. Leading health care companies have adopted Aptilon’s model, driving tens of thousands of high-quality rep-physician interactions averaging more than eight minutes in length. Aptilon provides the infrastructure necessary for sales representatives to build physician awareness, understanding and preference during all stages of a products life cycle, from pre-launch education through end stage support. For more information, visit
www.aptilon.com.

Forward-looking Statement
This news release contains forward-looking information. These statements relate to future events or future performance and reflect management's current expectations and assumptions. Such forward-looking statements reflect management's current beliefs and are based on information currently available to management of Aptilon. A number of factors could cause actual events, performance or results to differ materially from the events performance and results discussed in the forward-looking statements. These forward-looking statements are made as of the date hereof and Aptilon does not assume any obligation to update or revise them to reflect new events or circumstances.

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